Determination of Four Chromones in Saposhnikoviae Radix by Multi-components with Single Marker
10.3969/j.issn.1008-049X.2018.01.023
- VernacularTitle:一测多评法测定防风中4种色原酮类成分
- Author:
Lili WANG
1
;
Qiang LIAO
;
Ni OU
;
Riwei WEI
Author Information
1. 广西壮族自治区梧州食品药品检验所 广西梧州543002
- Keywords:
Multi-components with single marker;
Saposhnikovia Radix;
Chromones;
Relative correction factor
- From:
China Pharmacist
2018;21(1):96-100
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish a method for the simultaneous determination of four chromones in Saposhnikoviae Radix by multi-components with single marker ( QAMS) .Methods:An HPLC analysis was used to determine the contents of 4′-O-β-D-glucosyl-5-O-methylvisamminol , cimifugin and sec-O-glucosylhamaudol in Saposhnikoviae Radix.Prim-O-glucosylcimifugin was chosen as the single maker.The contents of 4 chromones in 10 batches of samples were determined by both external standard method and QAMS .The reliability and feasibility of the method were evaluated by the comparison of the quantitative results between the external standard meth -od and QAMS.Results:The relative correction factor (RCF) was perfect.The results calculated by the single marker were consistent with the results from the external standard method .Conclusion:The method with single marker is accurate and feasible to evaluate the quality of Saposhnikoviae Radix.
