Study on the Purification of Citral in Volatile Oil from Fructus Litseae by Molecular Distillation
10.3969/j.issn.1008-049X.2018.01.018
- VernacularTitle:分子蒸馏法纯化荜澄茄挥发油中柠檬醛的研究
- Author:
Leilei ZHAO
1
;
Junwei WU
;
Yong ZOU
;
Xinjun XU
Author Information
1. 中山大学药学院 广州510006
- Keywords:
Litsea cubeba(Lour.) Pers.;
Citral;
Molecular distillation;
GC;
Purification
- From:
China Pharmacist
2018;21(1):75-78
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the purification process of citral in volatile oil from Fructus Litseae by molecular distillation . Methods:The twice molecular distillation , GC and area normalization method were used for extracting citral , detecting the contents and describing the efficacy of purification , respectively .The mainly factor concerned was temperature .The conditions were as follows:the system pressure was 3000 Pa, the scraper speed was 300 r· min-1 , the feeding rate was 7.5 ml· min-1 and the distillation tem-perature was 45℃for the first time molecular distillation; the system pressure was 5 Pa, the scraper speed was 300 r· min-1 , the feeding rate was 7.5 ml· min-1 and the distillation temperature was 45℃ for the second time molecular distillation .GC was utilized under the following conditions:the sample injection was 1 μl, the column temperature was programmed from 70℃to 250℃, the split ratio was 1:100 and the flow rate of carrier gas was 1.0 ml· min-1 .Results: The content and yield of citral was up to 95.0％ and 87.5％, respectively.Conclusion:The method of twice molecular distillation in combination with GC to purify and detect citral is es -tablished in the work, which can provide reference for the research on the chemical components of Litsea cubeba(Lour.) Pers.and the preparation of citral .
