Application of Multi-element Fingerprints in the Study of Origin Traceability of Anemarrhenae Rhizoma
10.3969/j.issn.1008-049X.2018.01.014
- VernacularTitle:基于多元素指纹的知母产地溯源技术研究
- Author:
Hongkun ZHANG
1
,
2
;
Yuyao HUANG
;
Linyan PAN
;
Ruxi PENG
;
Jinsong ZHOU
;
Changda GUO
Author Information
1. 广州市香雪制药股份有限公司 广州510663
2. 亳州市沪谯药业有限公司
- Keywords:
Anemarrhenae rhizome;
Multi-element fingerprints;
Origin;
Discrimination analysis;
ICP-MS
- From:
China Pharmacist
2018;21(1):61-65
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the origin traceability of anemarrhenae rhizoma from Bozhou and Hebei based on multi-element fingerprints technology , and establish a discrimination model .Methods:The contents of 48 elements were determined by using induc-tively coupled plasma mass spectrometry ( ICP-MS) for 44 samples of anemarrhenae rhizome from Bozhou and Hebei province .Princi-pal component analysis ( PCA) and orthogonal partial least squares discrimination analysis ( OPLS-DA) were applied in the data analy-sis to screen out the significant elements .And then Fisher linear discrimination analysis was used to determine the origin of anemarrhe-nae rhizoma and the discrimination models were developed .Results:Two discrimination models were developed by the discrimination a-nalysis of the whole model method with nine significant elements identified by PCA and OPLS -DA, and 100％correct classification and 95.5％cross validation were achieved by the models .Conclusion: It is a promising approach to classify the geographical origin of anemarrhenae rhizome based on multi-element fingerprints analysis combined with multivariate statistical analysis .The discrimination models are good enough to be applied in the origin traceability of anemarrhenae rhizome.
