Optimization of High Pressure Steaming Processing Technology for Polygonum Multiflorum Thunb.by Box-Behnken Response Surface Methodology
10.3969/j.issn.1008-049X.2018.01.008
- VernacularTitle:Box-Behnken响应面法优化高压蒸法炮制何首乌工艺
- Author:
Xiaofei ZHANG
1
;
Qiuting GUO
Author Information
1. 陕西中医药大学药学院陕西省中药制药重点学科 陕西咸阳712000
- Keywords:
Polygonum multiflorum Thunb.;
High pressure steaming processing method;
Box-Behnken response surface method;
Polysaccharide;
Stilbene glucoside;
Normalized value
- From:
China Pharmacist
2018;21(1):33-37,47
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the high pressure steaming processing technology for Polygonum multiflorum Thunb.by Box-Behnken response surface methodology , and compare with the traditional processing .Methods:The effects of factors such as steaming temperature, steaming time and drying temperature on polysaccharide content , stilbene glucoside content and normalized value in Po-lygonum multiflorumThunb.were studied by Box-Behnken response surface methodology .The content differences of polysaccharides and stilbene glucoside between the high pressure steaming processed product and the traditional processed product were evaluated .Re-sul ts:The best high pressure steaming processing conditions for Poyl gonumm luitlfo urm Thunb .were as follows:the steaming tempera -ture was 1254.℃ , the steaming time was3.1 h, and the drying temperature was 52℃.The contents of polysaccharides and stilbene glycosides in Polygonum multiflorum Thunb.processed by the high pressure steaming method were 1.24-fold and 5.26-fold higher than those processed by the traditional method .Conclusion:Box-Behnken response surface method can be used to optimize the high pres-sure steaming processing for Polygonum multiflorum Thunb., and the method is simple and predictable .