Chemical Constituents of Endophytic Fungus Aconitum Transsectum from Alternaria Solani
10.3969/j.issn.1008-049X.2018.01.003
- VernacularTitle:直缘乌头内生真菌Alternaria solani化学成分研究
- Author:
Dan HE
1
;
Shuhui ZI
;
Yong SHEN
Author Information
1. 云南农业大学农学与生物技术学院 昆明650201
- Keywords:
Aconitum transsectum;
Alternaria solani;
Endophytic fungus;
Chemical constituents
- From:
China Pharmacist
2018;21(1):10-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of endophytic fungus Alternaria solani from Aconitum transsectum. Methods: The compounds were isolated and purified by column chromatography , and their structures were elucidated based on the spectroscopic analysis (1H-NMR, 13C-NMR and MS).Results:Totally 15 compounds were isolated from A.solani and characterized as 20-hydroxyl-ergosta-4,6,8(14),22-tetraen-3-one(1),ergone(2),stellasterin(3),episterol(4),ergosterol peroxide(5),cyclo(D)-Pro-(D)-Leu(6),cyclo-(L-Val-L-Pro)(7),cyclo-(S-Pro-S-Ile)(8),tentoxin(9),porrotoxin(10),7-dehydroxyl-zinniol(11),zinniol (12),8-zinniol methyl ether (13),3-methoxy-4-methyl-5-(3′,3′-dimethylallyloxy)-2-methoxymethyl benzoic acid (14) and pseudo-monas aeruginosa H2-sesquiterpene lactone (15).Conclusion: Totally 15 compounds are isolated from endophytic fungus Alternaria solani, and compounds 2-10 and 12-15 are isolated for the first time .