Antimicrobial Effectiveness of Domestic Lomefloxacin Hydrochloride Eye Drops
- VernacularTitle:国产盐酸洛美沙星滴眼剂抑菌效力考察
- Author:
Lei GAO
1
;
Huanhuan PANG
;
Xin MAO
;
Yanchun FENG
Author Information
1. 吉林省药品检验所 长春130000
- Keywords:
Lomefloxacin hydrochloride eye drops;
Antimicrobial agents;
Antibacterial efficacy
- From:
China Pharmacist
2017;20(11):2093-2095
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the antimicrobial effectiveness of lomefloxacin hydrochloride eye drops from 13 domestic manu-facturers. Methods:The antimicrobial effectiveness of lomefloxacin hydrochloride eye drops was tested based on the antimicrobial ef-fectiveness testing in Chinese Pharmacopoeia(2015 edition,volume 4). Results:The samples from 5 manufacturers could reach level A,those from 3 manufacturers were at level B, and those from 5 manufacturers did not comply with the specification. Conclusion:Some problems exist in the usage of antimicrobial agents in lomefloxacin hydrochloride eye drops from some Chinese manufacturers,and these manufacturers should optimize the type and concentration of antimicrobial agents according to the requirements of Chinese Phar-macopoeia combined with the corresponding prescriptions under the principle of minimum concentration while best effect.
