Adjustment and Analysis of Analgesic Regimen for One Ovarian Cancer Patient with Brain Metastases
- VernacularTitle:1例卵巢癌伴脑转移患者的疼痛治疗方案调整与分析
- Author:
Jinyu LIU
1
;
Xiaofang WANG
;
Ruxu YOU
Author Information
1. 华中科技大学同济医学院附属同济医院药学部 武汉430033
- Keywords:
Clinical pharmacists;
Ovarian cancer;
Brain metastases;
Analgesia;
Pharmaceutical intervention
- From:
China Pharmacist
2017;20(11):2031-2033
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To provide reference for the treatment of mixed pathological pain by analyzing the analgesic regimen for one ovarian cancer patient with brain metastases. Methods: The clinical pharmacists could conduct comprehensive and dynamic pain as-sessment,and supply the best evidence by consulting the related literatures and guidelines to assist the clinicians to formulate individu-alized administration regimen. Results: After comprehensive considering the clinical diseases, the characteristics and degree of the pain,the psychological status and the other factors,the analgesic regimen was finally adjusted to be a strong opioid combined with a tri-cyclic antidepressant,an anticonvulsant and a corticosteroid. Consequently, the patient obtained effective analgesic treatment without adverse reactions. Conclusion:The pain caused by ovarian cancer with brain metastasis is often severe and difficult to be treated. In clinics,comprehensive and dynamic pain assessment,standard titration of opioids and rational use of adjuvant drugs based on consider-ing patients' conditions are critical for controlling the pain as soon as possible and improving the quality of life of patients.
