Extraction Technology Optimization for Qige Granule by Orthogonal Design
- VernacularTitle:正交试验法优选芪葛颗粒的提取工艺
- Author:
Keer HUANG
1
;
Dongxiao LI
;
Yan LUO
;
Xuehong KE
Author Information
1. 广州中医药大学第一附属医院 广州510405
- Keywords:
Qige granule;
Astragaloside IV;
Puerarin;
Orthogonal design;
Comprehensive evaluation
- From:
China Pharmacist
2017;20(11):1976-1979
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the extraction technology of Qige granule. Methods:An HPLC method was established to de-termine the contents of astragaloside IV and puerarin in the extract of Qige granules. Based on the orthogonal design of L9(34),three factors including the water amount,decocting duration and extracting times were evaluated. Results:The best extraction process was as follows:adding 12-fold amount of water and extracting 3 times with 30 min for each time. Conclusion:The extraction technology opti-mized by the components evaluation is reasonable and practicable.
