Separation of Alkaloids from the Roots of Macleaya Cordata
- VernacularTitle:博落回根中生物碱的分离
- Author:
Kun YU
1
;
Feng XIANG
;
Zhixing QING
;
Peng YANG
;
Jianguo ZENG
Author Information
1. 浙江省立同德医院中药房 杭州310012
- Keywords:
Alkaloids;
Isolation;
Macleaya cordata
- From:
China Pharmacist
2017;20(11):1903-1906
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the alkaloids in Macleaya cordata. Methods:The compounds were isolated and purified by silica gel,recrystallization,and semi-preparative HPLC, and their strcuctures were confirmed by MS and NMR. Results: Nine alkaloids were obtained and identified as dihydrochelerythrine(1), 6-cyanodihydrosanguinarine(2), R-6-((R)-1-hydroxyethyl)dihydrochel-erythrine(3),8-demethyl-dihydrochelerythrine(4),cheilanthifoline(5),canadine(6),8-demethyl-chelerythrine(7),protopine(8) and allocryptopine(9). Conclusion:Compounds 4-6 are isolated from the genus of Macleaya for the first time.
