Application of zebrafish in field of pharmacy
10.3969/j.issn.1001-1978.2018.07.005
- VernacularTitle:斑马鱼在药学领域的应用研究
- Author:
Mei-Juan QI
1
;
Mei-Zhi SHI
;
Yong-Long HAN
Author Information
1. 上海海洋大学食品学院
- Keywords:
zebrafish;
drug metabolism;
traditional Chinese medicine;
toxicology;
drug screening;
regenerative drugs;
ap-plication
- From:
Chinese Pharmacological Bulletin
2018;34(7):903-906
- CountryChina
- Language:Chinese
-
Abstract:
Zebrafish (Danio rerio) is a simple biological labora-tory animal, with similar biological structure and physiological functions to mammals. Almost transparent embryos, in vitro de-velopment of embryos and up to 87% of human genetic similari- ties enable a wide application of zebrafish in the field of pharma-ceutical research. In this paper, we have studied the application of zebrafish in drug metabolism, the research of Chinese medi-cine, the evaluation of drug toxicology and safety, the screening of drugs and the discovery of new drugs, the research of regener- ative drugs, so as to provide new ideas of zebrafish in the field of pharmacy.
