Advances in constructing metastatic animal models of prostate cancer
10.3969/j.issn.1001-1978.2018.06.006
- VernacularTitle:前列腺癌转移动物模型特性的比较学分析
- Author:
Yu-Liang RAO
1
;
Zu-Yue SUN
Author Information
1. 上海市计划生育科学研究所药理毒理学研究室
- Keywords:
prostate cancer;
animal model;
tumor metastasis;
metastasis model;
evaluation method;
patient-derived tumor xen-ograft
- From:
Chinese Pharmacological Bulletin
2018;34(6):760-764
- CountryChina
- Language:Chinese
-
Abstract:
Prostate cancer is a common neoplasm of the genitou-rinary system for male, and tumor metastasis of prostate cancer is a common complication and a lethal factor. Researching on prostate cancer metastasis is very important for clinical research and treatment. Proper models of prostate cancer metastasis are important tools for the study of occurrence, progression, metas-tasis, and drug research for prostate cancer. This article intro-duces the common model of human prostate cancer metastasis, including the points of operation, evaluation, application of me-tastatic models and comparing the characteristics of various mod-els, to the benefit of researching and selecting models of prostate cancer.
