Research progress in role of myeloid cells in tumor microenvironment and its mechanisms
10.3969/j.issn.1001-1978.2018.02.001
- VernacularTitle:肿瘤微环境中髓样细胞对肿瘤的作用及机制研究进展
- Author:
Jia-Wei WU
1
;
Yu-Zhu CAO
;
Su-Yun YU
;
Ting-Ting ZHANG
;
Yu YANG
;
Wen-Xing CHEN
;
Ai-Yun WANG
;
Yin LU
Author Information
1. 南京中医药大学药学院
- Keywords:
tumor;
tumor microenvironment;
myeloid cells;
immune system;
mechanisms;
targeted therapy
- From:
Chinese Pharmacological Bulletin
2018;34(2):149-153
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,a large number of studies have shown that myeloid cells in tumor microenvironment play an important role in tumorigenesis and tumor progression.On one hand,myeloid cells can regulate human immune system;on the other hand,myeloid cells can influence tumor progression,metastasis and clinical treatments.In this review,we summarize the interaction between myeloid cells and tumors,discuss the effects of myeloid cells after recruited to tumor sites and its mechanisms,try to put forward clinical therapy targeting myeloid cells and provide references for the following research and clinical treatments.
