Risk Factors for Postoperative Nausea and Vomiting in Gynecological Patients Administered Prophylactic Antiemetics
10.12007/j.issn.0258-4646.2017.11.016
- VernacularTitle:预防性给予止吐药物的妇科患者发生术后恶心呕吐的危险因素
- Author:
Chenxi LIANG
1
;
Lidan LIU
;
Ying MU
;
Jing FENG
;
Ning ZHANG
;
Xiuying WU
Author Information
1. 中国医科大学附属盛京医院麻醉科
- Keywords:
postoperative nausea and vomiting;
gynecological surgery;
logistic regression analysis
- From:
Journal of China Medical University
2017;46(11):1032-1035,1044
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the risk factors for postoperative nausea and vomiting (PONV) in gynecological patients administered prophylactic antiemetics.Methods A total of 1 000 gynecological surgical cases were reviewed.Data on patient characteristics,anesthesia,surgeries,and 1st postoperative day nausea and vomiting were collected and analyzed statistically.Results Multivariate logistic regression analysis included a history of motion sickness,the use of an analgesic pump,the duration of anesthesia,and the use of neostigmine.The odds ratios (ORs),in decreasing order,were that of a history of motion sickness [OR =1.953,95％ confidence interval (CI):1.404-2.716],the use of neostigmine (OR =1.831,95％ CI:1.203-2.786),the use of an analgesic pump (OR =1.472,95％ CI:1.017-2.129),and the duration of anesthesia (OR =1.256,95％ CI:1.058-1.492).The predictive model was described by the following equation:P=1/(1+e(1623-0.669X1-0.386X2-0.228X3+0.605X4)).Tne predictive accuracy of this model for the incidence of PONV in gynecological patients was 70.6％,and the area under the receiver operating characteristic curve for the predictive result was 0.642.Conclusion The independent risk factors for PONV in gynecological patients administered prophylactic antiemetics are a history of motion sickness,the use of neostigmine,the use of an analgesic pump,and the duration of anesthesia,in decreasing order of significance.
