Correlation between Ischemia-modified Albumin Levels and Coronary Artery Lesions in Patients with Acute Coronary Syndrome
10.12007/j.issn.0258-4646.2017.11.011
- VernacularTitle:急性冠状动脉综合征患者缺血修饰白蛋白水平与冠状动脉病变程度的相关性研究
- Author:
Jing ZI
1
;
Lujiao YU
;
Zixin ZHANG
Author Information
1. 民航总医院心内科
- Keywords:
acute coronary syndrome;
ischemia modified albumin;
Gensini score
- From:
Journal of China Medical University
2017;46(11):1009-1012
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the correlation between ischemia-modified albumin (IMA) levels and severity of coronary artery lesions in patients with acute coronary syndrome (ACS).Methods This study included 51 in-hospital patients diagnosed as having ACS.All patients had undergone coronary angiography and received the standard treatment for coronary heart disease.Meanwhile,we included 10 healthy volunteers as the control group.Coronary angiography reports were collected,Gensini scores were calculated,and serum IMA levels were measured.Results The IMA levels of patients with ACS were higher than those of the controls (P ＜ 0.05).However,when divided by the degree of coronary artery stenosis,number of vessel lesions,and Gensini scores,the IMA levels showed no significant difference between the groups.The IMA levels were not related with the Gensini scores.The moderate group had a low ratio of TIMI flow grade 3.Conclusion Patients with ACS had higher IMA levels.We found no correlation between IMA level and coronary artery lesions.IMA level may not accurately reflect the severity of coronary artery lesions.Increased IMA level may indicate the unstable status of ischemia.
