Therapeutic Efficacy of Shengxuening Tablets in the Treatment of Iron-deficiency Anemia during Pregnancy:A Meta-analysis
10.6039/j.issn.1001-0408.2018.12.28
- VernacularTitle:生血宁片治疗妊娠期缺铁性贫血疗效的Meta分析
- Author:
Fan CHEN
1
;
Weiwei LIU
;
Qiaoyan LIU
;
Shiyi CAO
Author Information
1. 华中科技大学同济医学院公共卫生学院
- Keywords:
Shengxuening tablets;
Iron-deficiency anemia during pregnancy;
Randomized controlled trial;
Meta-analysis
- From:
China Pharmacy
2018;29(12):1707-1710
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate therapeutic efficacy of Shengxuening tablets in the treatment of iron-deficiency anemia during pregnancy,so as to provide evidence for clinical decisions. METHODS:Retrieved from CNKI,Wanfang,VIP and PubMed,clinical randomized controlled trials(RCTs)about Shengxuening tablets in the treatment of iron-deficiency anemia during pregnancy were collected during 2008-2018. After screening literatures and extracted information, the literature quality was evaluated by using improved Jadad scale. Meta-analyses was performed by using Stata 12.0 software. RESULTS:A total of 11 RCTs were included,inulving 1 617 patients. Total response rate of Shengxuening tablets was significantly higher than those of ferrous sulfate [OR＝8.73,95%CI(2.964,25.69),P＜0.05],ferrous succinate [OR＝1.86,95%CI(1.04,3.33),P＜0.05] and dietory conditioning [OR＝3.43,95%CI(2.08,5.66),P＜0.05],with statistical significance. CONCLUSIONS:Therapeutic efficacy of Shengxuening tablets is significantly better than that of routine iron supplements in the treatment of iron-deficiency anemia during pregnancy.
