Study on Chemical Constituents in Ethanol Extract from the Stem of Miao Medicine Rubus multibracteatus
10.6039/j.issn.1001-0408.2018.12.14
- VernacularTitle:苗药大乌泡茎乙醇提取物的化学成分研究
- Author:
Shijie DU
1
;
Guoning ZHOU
;
Laidi YANG
;
Zhaoyan WANG
Author Information
1. 铜仁学院材料与化学工程学院
- Keywords:
Miao medicine;
Rubus multibracteatus;
Stem;
Ethanol extract;
Chemical constituent;
Structure identification
- From:
China Pharmacy
2018;29(12):1644-1647
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the chemical constituents in ethanol extract from the stem of Miao medicine Rubus multibracteatus. METHODS:The ethanol extract from the stem of Miao medicine R. multibracteatus was isolated and purified by silica gel column,preparative liquid chromatography and Sephadex LH-20 gel column,etc. The structure of compounds were analyzed and identified according to physicochemical properties and spectrum data(MS,hydrogen spectrum and carbon spectrum). RESULTS:Ten compounds were isolated from the ethanol extract of R. multibracteatus stem,i.e. 5,4′-dihydroxy-8-(3,3-dimethylally)-2″, 2″-dimethylpyrano [5,6∶6,7] isoflavone(1),3-hydroxy-1-(4′-hydroxy-3′-methoxyphenyl)propan-1-one(2),3β-hydroxysitost-5-en-7-one (3),Lupeol(4),Coniferaldehyde(5),E-p-hydroxy-coumaric acid(6),Genistein(7),1-O-p-coumaroylglycerol(8),Scopoletin(9), and Kaempferol(10). CONCLUSIONS:Compound 1-9 are isolated from the plants of R. multibracteatus for the first time,and Compound 2,5,8 are isolated from the plants of Rubus L. for the first time. The study lays the foundation for further development and utilization of R. multibracteatus.
