Optimization of Extraction Technology of Shenqi Fukang Granules by Orthogonal Test
10.6039/j.issn.1001-0408.2018.10.09
- VernacularTitle:正交试验优化参芪妇康颗粒的提取工艺
- Author:
Zhen SUN
1
;
Ying ZHANG
;
Jie WANG
;
Mingcong CHEN
;
Zuguang HUANG
;
Huahong GAO
Author Information
1. 三亚市妇幼保健院
- Keywords:
Shenqi fukang granules;
Extraction technology;
Orthogonal test;
Yield of drug extract;
Content of ethanol extract
- From:
China Pharmacy
2018;29(10):1332-1334
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize extraction technology of Shenqi fukang granules. METHODS:Single factor method was used to investigate water multiple at first time using water absorption as index,soaking time using yield of dry extract as index. Based on single factor test,by weighted comprehensive scoring method,using the yield of dry extract and the content of 75％ ethanol extraction as indexes,extraction time,water multiple and extraction times as factors,L9(34) orthogonal test was used to optimize water extraction technology of Shenqi fukang granules. Validation test was conducted. RESULTS:The optimal water extraction technology included 8-fold water (L/kg), extracting for 3 times, 1 h each time. CONCLUSIONS:The optimized extraction technology is stable and controllable in quality,and can provide reference for industrial production of Shenqi fukang granules.
