Comparison of the Content of Total Saponins and Platycodin D in Platycodon grandiflorum from Sichuan of Different Cultivated Years
10.6039/j.issn.1001-0408.2018.09.23
- VernacularTitle:不同栽培年限川桔梗中桔梗总皂苷和桔梗皂苷D的含量比较
- Author:
Xinyi LI
1
;
Ling CHEN
;
Yuying MA
;
Wei DENG
Author Information
1. 成都中医药大学药学院/中药资源系统研究与开发利用省部共建国家重点实验室培育基地
- Keywords:
Platycodon grandiflorum from Sichuan;
Total saponins;
Platycodin D;
Cultivated years;
Content determination
- From:
China Pharmacy
2018;29(9):1249-1252
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE：To establish a method for content determination of total saponins and platycodin D in Platycodon grandiflorum from Sichuan and investigate the difference of 2 indexes in P. grandiflorum from Sichuan of different cultivated years. METHODS：The content of total saponins in P. grandiflorum from Sichuan was determined by UV spectrophotometry. The content of platycodin D was determined by HPLC. The contents of total saponins and platycodin D were compared among each 10 samples of annual，biennial and triennial P. grandiflorum from Sichuan. RESULTS：Average contents of total saponins in annual，biennial and triennial P. grandiflorum from Sichuan were 2.47％ ，3.01％ ，2.47％ ，respectively；average contents of platycodin D were 0.23％，0.27％，0.33％，respectively. The contents of 2 indexes in annual P. grandiflorum from Sichuan were in relative low level， while the content total saponins in biennial P. grandiflorum from Sichuan was the highest；the content of platycodin D in triennial P. grandiflorum was the highest. CONCLUSIONS：The contents of indexes are different among P. grandiflorum from Sichuan of different cultivated years. But there is no correlation between them. It is suggested to select biennial and triennial P. grandiflorum from Sichuan.
