Study on Chemical Constituents of Ethanol Extract from Cirtus aurantium
10.6039/j.issn.1001-0408.2018.04.07
- VernacularTitle:枳实药材乙醇提取物的化学成分研究
- Author:
Kezhong DENG
1
;
Meiyan CHANG
;
Qi ZONG
;
Ying XIONG
Author Information
1. 江西中医药大学药学院
- Keywords:
Cirtus aurantium;
Chemical constituent;
Structural identification;
Ethanol extract;
Citrus L.
- From:
China Pharmacy
2018;29(4):458-460
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the chemical constituents of ethanol extract from Cirtus aurantium. METHODS: The ethanol extract of C. aurantium was isolated and purified by silica gel column, open ODS column, preparation liquid chromatography, HW-40F gel column and macroporous resin column. The structure of compounds was analyzed and identified according to physicochemical properties and spectral data (mass spectrum, hydrogen spectrum, carbon spectrum). RESULTS: Eight compounds were isolated from ethanol extract of C. aurantium, i. e. Rimboxo (1), Thymidine (2), Uracil (3), Cyclo-(Leu1-Ile2-Ala3-Thr4-Gly5-Thr6-Phe7) (4), Cyclo- (Leu1-Leu2-Pro3-Tyr4-Gly5-Ser6-Pro7) (5), Meranzin hydrate-β-D-glucoside (6), Umbelliferone (7), Linaloyl glucoside (8). CONCLUSIONS: Compound 1, 2, 3, 8 are isolated from Citrus L. for the first time, compound 4, 5, 6 were isolated from C. aurantium for the first time. The study lays the foundation for quality evaluation of C. aurantium.
