Study on Chemical Constituents of 70％ Ethanol Extract of Breynia fruticosa
10.6039/j.issn.1001-0408.2017.36.27
- VernacularTitle:黑面神药材70％乙醇提取部分的化学成分研究
- Author:
Weiwen PENG
1
;
Wensheng HE
;
Mengying JI
;
Zhuqiang WANG
Author Information
1. 广州中医药大学附属中山中医院药学部
- Keywords:
Breynia fruticosa;
Chemical constituents;
Flavone;
Lignan
- From:
China Pharmacy
2017;28(36):5144-5147
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the chemical constituents of 70％ ethanol extract of Breynia fruticosa.METHODS:The 70％ ethanol extract of B.fruticosa were isolated and purified by D101 macroporous resin,silica gel column chromatography,RP-silica gel column chromatography,Sephadex LH-20 gel column chromatography,preparative HPLC.The structure of compound was analyzed and identified according to physicochemical characters and spectral data.RESULTS:10 compounds were separated from 70％ ethanol extract of B.fruticosa,such as Luteolin (1),Quercetin (2),Kaempferol (3),Tiliroside (4),(+)-Lyoniresinol (5),(+)-Isolariciresinol (6),(+)-Nortrachelogenin (7),(+)-Syringaresinol (8),Icariol A2 (9),5,5'-Dimethoxy-7-oxolariciresinol (10),respectively.CONCLUSIONS:Ten compounds are isolated from this plant for the first time.The study play the found for quality evaluation of 70 ％ ethanol extract of B.fruticosa.
