Advances in drug delivery systems for the treatment of liver fibrosis
10.11665/j.issn.1000-5048.20180302
- VernacularTitle:治疗肝纤维化药物递送系统研究进展
- Author:
Qianqian FAN
1
;
Lei XING
;
Jianbin QIAO
;
Chenglu ZHANG
;
Hulin JIANG
Author Information
1. 中国药科大学药学院药剂系
- Keywords:
liver fibrosis;
anti-fibrosis;
nano-drug delivery systems;
targeting strategies
- From:
Journal of China Pharmaceutical University
2018;49(3):263-271
- CountryChina
- Language:Chinese
-
Abstract:
Liver fibrosis is a major disease that affects human health. Currently,drugs used for the treatment of hepatic fibrosis have such problems as low drug solubility,lack of liver specificity and possible occurrence of side-effects. In order to improve the anti-fibrosis therapeutic efficacy,various nano-drug delivery systems and targeting strategies are explored in liver fibrosis therapy. This review summarizes the drug delivery systems and targeting strategies that have been applied to liver fibrosis therapy in recent years from the types of carriers and modified ligands,which serve as a basis of designing safe and effective drug delivery systems for liver fibrosis therapy.
