Application of event-related brain potential in intelligence impairment assessment after craniocerebral trauma
10.3760/cma.j.issn.1674-6554.2018.08.015
- VernacularTitle:事件相关电位在颅脑外伤后智能损害评估中的应用
- Author:
Suling CHEN
1
;
Ziye HUANG
;
Suilin JIA
;
Xiaofan CHEN
;
Yalin CHEN
;
Xingshi CHEN
Author Information
1. 温州市第七人民医院精神科
- Keywords:
Event-related potential;
Craniocerebral trauma;
Intelligence impairments;
Judicial expertise
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2018;27(8):749-752
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of event-related potentials (ERPs) in patients with intelligence impairments after craniocerebral trauma.Methods 60 patients with intelligence impairments after craniocerebral trauma were enrolled as case group,and 60 healthy subjects were enrolled as control group.EEG instrument was used to record P300 and P50 of the two groups and the differences in P300 and P50 components were compared.Results There are significant differences between case group and control group in latency of P300 ((440.430 ± 77.367) ms vs (342.928 ± 36.175) ms,P＜ 0.01),and case group showed decreased amplitude ((12.692±8.152) μV vs (18.138±6.590) μV,P＜0.01).The S2-P50 amplitude of case group was significantly higher than that of control group ((3.75± 1.59) μV vs (2.42±1.43) μV,P＜0.01).In addition,the S2-P50 amplitude/S1-P50 amplitude ratio of case group was higher than that of the control group,and the difference was statistically significant (0.78±0.54 vs 0.46±0.18,P＜0.01).The latency and amplitude of P300 were significantly correlated with the total score of WAIS-RC (r=-0.31,P＜0.01;r=0.17,P＜0.01);The amplitude of S2-P50 and the ratio of S2-P50 amplitude to S1-P50 amplitude were significantly negatively correlated with the total score of WAIS-RC (r=-0.33,P＜0.01;r=-0.45,P＜0.01).Conclusion P300 and P50 components of ERP can provide references for judicial expertise to evaluate intelligence impairments after craniocerebral trauma.
