The effect of depression on morning blood pressure surge in maintenance hemodialysis patients with hypertension
10.3760/cma.j.issn.1674-6554.2018.05.009
- VernacularTitle:抑郁情绪对维持性血液透析高血压患者血压晨峰的影响
- Author:
Fangfang HU
1
;
Yong DANG
;
Yong WANG
;
Xiaoyan LI
;
Huina CHEN
;
Bo GAO
;
Sen LIU
Author Information
1. 安阳市人民医院肾内科
- Keywords:
Depression;
Maintenance hemodialysis;
Morning blood pressure surge
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2018;27(5):426-429
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of depression on morning blood pressure surge ( MBPS) in maintenance hemodialysis( MHD) patients with hypertension. Methods 67 MHD patients with hypertension were included in this study.All clinical data were collected,and ambulatory blood pressure mo-nitor was used to monitor patient''''''''s blood pressure in 24 hours.Self-rating depression scale(SDS) was used to survey 67 MHD patients,and multivariable logistic regression was conducted to determine independent risk factors for morning hypertension in MHD patients with hypertension. Results There were 14 depression pa-tients in non-morning hypertension group ( 35. 0％) , 18 depression patients in morning hypertension group (66.7％),and the difference was significant(χ2=6.479,P=0.011).In addition correlation analysis showed that age(r=0.027,P=0.044),24 h systolic pressure(r=0.284,P=0.020),24 h diastolic pressure(r=0.278,P=0.023),fasting blood-glucose (r=0.293,P=0.039),low-density lipoprotein cholesterol (r=0.345,P=0.016),and the standard score of SDS(r=0. 276,P=0.024)were significantly correlated with MBPS .Furthermore,multivariable logistic regression showed that the standard score of SDS(OR=1.101,95％CI=1.018-1.191,P=0.016) ,24 h diastolic pressure ( OR=1.070,95％CI=1.007-1.136,P=0.028) and fast-ing blood-glucose (OR=2.127,95％CI=1.118-4.049,P=0.022)were independent risk factors for morning hypertension in MHD patients with hypertension ( OR=1. 101, 95％CI:1. 018-1. 191, P=0. 016 ) . Conclu-sion Depression,24 h diastolic pressure and fasting blood-glucose can increase the risk of morning blood pressure surge in patients with MHD hypertension.
