Feasibility and Effectiveness of Percutaneous Balloon Mitral Valvuloplasty Under Echocardiographic Guidance Only
10.3969/j.issn.1000-3614.2018.11.009
- VernacularTitle:单纯超声心动图引导下经皮二尖瓣球囊成形术的可行性及有效性研究
- Author:
Cheng WANG
1
;
Wen-Bin OUYANG
;
Feng-Wen ZHANG
;
Gai-Li GUO
;
Yao LIU
;
Guang-Zhi ZHAO
;
Yong-Quan XIE
;
Xiang-Bin PAN
Author Information
1. 中国医学科学院 北京协和医学院 国家心血管病中心 阜外医院 心外科
- Keywords:
Rheumatic mitral stenosis;
Balloon mitral valvuloplasty;
Echocardiography;
Percutaneous intervention
- From:
Chinese Circulation Journal
2018;33(11):1080-1084
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: The present first-in-human study aimed to assess the feasibility of percutaneous balloon mitral valvuloplasty (PBMV) for the treatment of isolated mitral stenosis (MS) under echocardiography guidance only. Methods: Data were obtained from 24 consecutive patients with severe MS, who underwent PBMV from October 2016 to October 2017 under the guidance of echocardiography only. Outpatient follow-up including chest radiography, electrocardiography, and transthoracic echocardiography was conducted at 1, 3, 6 and 12 months post procedure. Results: PBMV was successful in all 24 patients under echocardiography guidance without radiation and contrast agent. Mitral transvalvular pressure gradient derived invasive catheterization measurement dropped from(15.0±5.1) mmHg to (6.7±2.9) mmHg (P<0.01). Mitral valve area increased from (0.8±0.1) cm2at pre-PBMV to (1.7±0.1) cm2post-PBMV (P<0.01). Mean balloon diameter was (26.7±1.2) mm. Mild mitral regurgitation developed in 8 patients. Mean follow-up duration was (7.4±3.1) months. At the last follow-up, mitral valve area remained high (1.6±0.1) cm2and mean transmitral pressure gradient remained low (9.0±4.3) mmHg. No pericardial effusion or peripheral vascular complications occurred. Conclusions: In this patient cohort, PBMV could be successfully performed with echocardiography as the single imaging guidance modality, this procedure is safe and effective and avoids the radiation exposure and contrast agent use.