Risk Predictors of New-onset Atrial Fibrillation After Coronary Artery Bypass Grafting
10.3969/j.issn.1000-3614.2018.10.007
- VernacularTitle:冠状动脉旁路移植术后新发心房颤动的危险因素分析
- Author:
Lei XI
1
;
Zheng-Qing WANG
;
Zhi-Gang LIU
;
Shao-Jie LIANG
;
Lei TENG
Author Information
1. 泰达国际心血管病医院 心脏外科
- Keywords:
Atrial fibrillation;
Coronary artery bypass grafting;
Risk factors
- From:
Chinese Circulation Journal
2018;33(10):969-972
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: This study aims to determine the risk factors of new-onset atrial fibrillation (AF) in patients who underwent isolated coronary artery bypass grafting (CABG) to provide evidences for the prevention and treatment of new-onset AF after CABG. Methods: Between January 2015 and May 2016, a total of 602 patients who underwent CABG in our department were retrospectively analyzed. The patients were divided into the AF group and the non-AF group, according to the occurrence of post-operative AF. A comparative analysis was performed on the general characteristics and perioperative data of the patients. Univariate and multivariate logistic analysis was used to identify the predictors of new-onset AF after CABG. Results: 128 patients developed AF post CABG. Left ventricular ejection fraction was significantly lower in AF group than that in non-AF group (P<0.05), while the left ventricular end diastolic diameter (LVEDD) and left atrium diameter (LAD) were significantly larger in AF group than in non-AF group (all P<0.05). Moreover, mechanical ventilation time and ICU stay were significantly longer in AF group than in non-AF group (both P<0.05). Logistic univariate analyses showed that a history of hyperlipidemia (OR=1.738, P=0.019), higher left atrium diameter (OR=1.097, P=0.001), higher NYHA classes (OR=1.689, P=0.004), and use of nitrates (OR=2.196,P=0.030) were associated with new-onset AF after CABG. After adjusting for age and gender, multivariate analyses showed that higher NYHA classes (OR=1.597, P=0.007) and LAD enlargement (OR=1.113, P=0.0001) remained as independent risk factors for new-onset AF after CABG. Conclusions: Higher NYHA classes and LAD enlargement are independent risk factors for new-onset AF after CABG.