Safety and Efficacy Comparison of Transradial Versus Transfemoral Percutaneous Coronary Intervention in Female Patients
10.3969/j.issn.1000-3614.2018.10.005
- VernacularTitle:女性患者经桡动脉与经股动脉行经皮冠状动脉介入治疗的安全性和疗效比较
- Author:
Yi XU
1
;
Chen JIN
;
Shu-Bin QIAO
;
Yong-Jian WU
;
Hong-Bing YAN
;
Ke-Fei DOU
;
Bo XU
;
Jin-Gang YANG
;
Yue-Jin YANG
Author Information
1. 中国医学科学院 北京协和医学院 国家心血管病中心 阜外医院 冠心病中心
- Keywords:
Percutaneous coronary intervention;
Transradial intervention;
Transfemoral intervention;
Women
- From:
Chinese Circulation Journal
2018;33(10):958-963
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: This study sought to compare both the safety and efficacy of transradial (TRI) versus transfemoral (TFI) approach in women undergoing percutaneous coronary intervention (PCI) in China. Methods: We retrospectively analyzed data from 5 067 women undergoing PCI in Fuwai Hospital, Beijing, China between 2006 and 2011. 4 105 patients underwent TRI and 962 patients underwent TFI. A One-to-one propensity score matching (PSM) was performed to control for potential biases. A total of 897 pairs were matched. Results: After controlling for confounders using PSM, baseline and procedural characteristics were well-balanced between TRI and TFI groups. Patients undergoing TRI had significantly fewer major post-PCI bleeding (1.0% vs 3.5%, P<0.001) and access site complications (8.5% vs 19.7%,P<0.001) after PSM. There was no statistical differences in the incidence rates of major adverse cardiac events (a composite of cardiac death, myocardial infarction, and target vessel revascularization) during hospitalization (P>0.05). Multiple logistic regression analysis showed that TRI was an independent predictor of reduced major bleeding (OR=0.64, 95%CI: 0.54-0.76, P<0.001) and access site complications (OR=0.67, 95%CI:0.61-0.74, P<0.001). Conclusions: Our result show that TRI is related to reduced major bleeding and access site complications as compared to TFI in Chinese female patients undergoing PCI.
