Relationship Between the Systolic Blood Pressure Variability and Glomerular Filtration Rate in the Elderly
10.3969/j.issn.1000-3614.2018.06.015
- VernacularTitle:老年人收缩压变异性与肾小球滤过率的关系
- Author:
Yu-Zhen WANG
1
;
Lu SONG
;
Shou-Ling WU
;
Xiu-Yan WANG
Author Information
1. 开滦总医院 老年病科
- Keywords:
Elderly;
Systolic blood pressure variability;
Glomerular filtration rate
- From:
Chinese Circulation Journal
2018;33(6):591-595
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To investigate the correlation between the systolic blood pressure variability and glomerular filtration rate in the elderly. Methods:From retired employees who participated in the third time physical examination of Kailuan group to underwent 24-hour ambulatory blood pressure monitoring. A total of 3 064 subjects aged over 60 years were recruited by cluster sampling method. 2 464 participants who met the inclusion were included and tested the renal function, with estimated glomerular filtration rate (eGFR) as indicators of renal function evaluation. Finally, 1 382 cases up to the standard. Multiviate regression models were performed to analyze the correlataion beteen short-term MMD and eGFR. Results:The mean age of 1 382 participants was (67.16±5.86) years, and 905 individuals (65.5%) were male. Levels of eGFR decreased with the increased of MMD (P＜0.05). Pearson correlation analysis indicated that eGFR was positively correlated with 24 hr-MMD、day-MMD and night-MMD(P＜0.05). Multivarite linear regrsssion analysis indicated that 24 hr-MMD、day-MMD were correlated with eGFR. Conclusions:24 hr-MMD、day-MMD are correlated with eGFR.
