Analysis on the Correlation Between ECG Parameters and Cardiac Function in Severe Triple Coronary Vessel Disease Patients Without Myocardial Infarction
10.3969/j.issn.1000-3614.2018.05.006
- VernacularTitle:无心肌梗死的严重三支血管病变患者心功能不全与其心电图指标的相关性分析
- Author:
Fei HAN
1
;
Zi-Qing YU
;
Sheng-Mei QIN
;
Ling-Yan FANG
;
Ming-Hui LI
;
Yan-Gang SU
;
Jun-Bo GE
Author Information
1. 复旦大学附属中山医院 心内科 上海市心血管病研究所
- Keywords:
Triple vessel disease;
Cardiac dysfunction;
QRS
- From:
Chinese Circulation Journal
2018;33(5):441-445
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To analyze the correlation between systolic cardiac insufficiency and ECG parameters of patients with triple-vessel disease(left anterior descending artery, left circumflex artery and right coronary artery showed ≥ 70% of diameter stenosis), but without history of myocardial infarction. Methods: A total of 96 triple-vessel disease patients without prior myocardial infarction who underwent coronary angiography examination between 2017-03-01 and 2017-07-05 in Zhongshan hospital were recruited in this study. According to LVEF, patients were divided into the normal cardiac function group (78 patients with LVEF ≥ 50%) and the reduced LVEF group (18 patients with LVEF < 50%). The Receiver Operating Characteristic (ROC) curve was applied to test optimal cut-off value of the ECG parameters and logistics regression analysis was utilized to determine the correlation between ECG indices with cardiac insufficiency. Results: A small percentage (18.8%) triple-vessel disease patients without prior myocardial infarction developed cardiac insufficiency. QRS duration, QTc duration were all significantly increased in patients with cardiac dysfunction) compared with patients with normal cardiac function (P < 0.05). ROC curve indicated good predictive efficacy to systolic cardiac insufficiency with HR > 70.5 bpm (sensitivity 81.3%, specificity 58.9%), QRS > 97.5 ms(sensitivity 82.4%, specificity 67.5%), QTc > 425 ms (sensitivity 93.8%, specificity 41.1%). Logistic multivariate regression analysis showed that QRS >97.5 ms(OR=7.577, 95%CI:1.094~52.490,P =0.030) was significantly correlated with systolic cardiac insufficiency. Conclusions: For triple-vessel disease patients without prior myocardial infarction, wider QRS in the resting ECG may indicate cardiac insufficiency.
