Comparison of Two Occlusion Devices for Treating Cryptogenic Stroke Patients Combining Patent Foramen Ovale and Large Right to Left Shunt
10.3969/j.issn.1000-3614.2018.04.017
- VernacularTitle:两种不同封堵器对不明原因脑卒中合并大量右向左分流患者卵圆孔未闭的疗效对比
- Author:
Wen-Juan LIU
1
;
Yu-Shun ZHANG
;
Ge-Sheng CHENG
;
Ya-Juan DU
;
Lu HE
;
Xing-Ye WANG
;
Xue-Gang XIE
Author Information
1. 西安交通大学第一附属医院 结构性心脏病科
- Keywords:
Foramen ovale,patent;
Stroke;
Occlusion device
- From:
Chinese Circulation Journal
2018;33(4):385-389
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: To compare the effect of 2 different occlusion devices for treating cryptogenic stroke (CS) patients combining patent foramen ovale (PFO) and large right-to-left shunt (RLS). Methods: A total of 123 CS patients combining PFO and large RLS treated in our hospital from 2013-05 to 2016-08 were enrolled. All patients received percutaneous PFO interventional closure, based on different occlusion devices, the patients were divided into 2 groups: Cardi-O-fix PFO occluder group, n=80 and Amplatzer PFO occluder group, n=43. CS diagnosis was confirmed by 3 experienced neurologists via medical imaging examination; PFO and large RLS were diagnosed by transthoracic echocardiography and right heart contrast echocardiography. The baseline features, clinical symptoms, operation and follow-up data were reviewed to observe the efficacy of 2 occlusion devices. Results: Each group had 1 patient suffered from paroxysmal atrial fibrillation after the operation; 1 patient in Cardi-O-fix PFO occluder group had inguinal hematoma. No stroke recurrence, no death during follow-up period; the residual shunt was similar between 2 groups. Conclusions: PFO occlusion was beneficial for preventing stroke recurrence in CS patients combining PFO and large RLS. The safety and efficacy were similar in Cardi-O-fix and Amplatzer PFO occlusion devices.
