Impact of Bundle Branch Block on Long-term Prognosis in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention
10.3969/j.issn.1000-3614.2018.02.006
- VernacularTitle:束支传导阻滞对冠状动脉介入治疗后急性冠状动脉综合征患者长期预后影响的研究
- Author:
Si-Da JIA
1
;
Yi YAO
;
Chen HE
;
Xiao-Fang TANG
;
Ying SONG
;
Jing-Jing XU
;
Ping JIANG
;
Huan-Huan WANG
;
Lin JIANG
;
Xue-Yan ZHAO
;
Zhan GAO
;
Yue-Jin YANG
;
Shu-Bin QIAO
;
Run-Lin GAO
;
Bo XU
;
Jin-Qing YUAN
Author Information
1. 北京协和医学院 中国医学科学院 国家心血管病中心 阜外医院 心内科
- Keywords:
Percutaneous coronary intervention;
Bundle branch block;
Acute coronary syndrome
- From:
Chinese Circulation Journal
2018;33(2):129-133
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the impact of bundle branch block (BBB) on acute coronary syndrome (ACS) prognosis in patients after percutaneous coronary intervention (PCI). Methods: A total of 6 429 ACS patients received PCI in our hospital from 2013-01 to 2013-12 were enrolled. According to BBB diagnosis at discharge, the patients were divided into 2 groups: BBB group, n=159 and Non-BBB group, n=6 270. The incidences of 2-year major adverse cardio and cerebral-vascular events (MACCE) including all-cause death, cardiac death, myocardial infarction, revascularization, in-stent thrombosis and stroke were compared between 2 groups; relationship between existing BBB and clinical outcomes was assessed. Results: Compared with Non-BBB group, BBB group had the elder age (62.97±11.37) years vs (58.26±10.36) years, lower BMI (25.31±3.02) vs (25.89±3.20), decreased glomerular filtration rate (86.89±16.15)ml/min vs (91.05±15.53)ml/min and LVEF (59.27±9.86)% vs (62.37±7.36) %, all P<0.05; other baseline condition, angiographic and interventional features were similar between 2 groups, all P>0.05. During 2-year follow-up period, compared with Non-BBB group, BBB group showed the higher incidences of cardiac death (2.5% vs 0.7%) and in-stent thrombosis (3.1% vs 0.8%), both P<0.05; other incidences of MACCE were similar between 2 groups, all P>0.05. With adjusted propensity score matching, 2-year incidence of MACCE was similar between 2 groups, P>0.05; 2-year incidences of MACCE in BBB group including LBBB and RBBB were similar to Non-BBB group, P>0.05. Cox regression analysis revealed that BBB was not related to ACS prognosis after PCI. Conclusion: BBB was not an independent risk factor for long-term MACCE occurrence in ACS patients after PCI.
