Relationship Between Monocyte to HDL-Cholesterol Ratio and Thrombus Burden in Patients With ST-segment Elevation Myocardial Infarction
10.3969/j.issn.1000-3614.2018.01.008
- VernacularTitle:单核细胞/高密度脂蛋白胆固醇比值与急性ST段抬高型心肌梗死患者血栓负荷的关系
- Author:
Ya-Fei HE
1
;
Wen-Hua LIN
;
Yu-Jie LU
;
Jing-Jing LIU
;
Rui JING
Author Information
1. 泰达国际心血管病医院 心内科
- Keywords:
Myocardial infarction;
Monocyte to HDL-C ratio;
Thrombophilia
- From:
Chinese Circulation Journal
2018;33(1):46-49
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the relationship between monocyte to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) in patients with ST-segment elevation myocardial infarction(STEMI) in order to explore the predictive value of MHR in thrombus burden level in STEMI patients. Methods: A total of 357 STEMI patients treated in our hospital from 2015-01 to 2016-12 were enrolled. Thrombus burden was confirmed by angiography and the patients were divided into 2 groups: Low thrombus burden group, n=156 and High thrombus burden group, n=201. MHR was compared between 2 groups; the predictive value of MHR in thrombus burden level was studied by multivariate Logistic regression analysis and ROC curve assessment. Results: MHR was higher in High thrombus burden group than that in Low thrombus burden group [M (Q1, Q3) 25.4 (13.5, 44.6) vs 16.0 (9.2, 22.1)], P<0.001; multivariate Logistic regression analysis indicated that MHR was the independent predictor for high thrombus burden occurrence (OR=1.067, 95％ CI 1.031-1.105), P<0.001; the area under ROC curve for MHR was 0.688 in STEMI patients. Conclusion: MHR was the independent predictor for high thrombus burden occurrence in STEMI patients.
