Distribution Features of Microvolt T-wave Alternation in Coronary Artery Disease Patients With MTWA Changes After Revascularization
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1000-3614.2018.01.007
   		
        
        	
        		- VernacularTitle:冠心病患者运动平板试验中微伏级T波电交替分布特征及其在血运重建后的变化
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Ting-Ting LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jun YAN
			        		
			        		;
		        		
		        		
		        		
			        		Xiao-Qin HU
			        		
			        		;
		        		
		        		
		        		
			        		Wu XU
			        		
			        		;
		        		
		        		
		        		
			        		Yuan LU
			        		
			        		;
		        		
		        		
		        		
			        		Zhi-Rong WANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 徐州医科大学附属医院 心内科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Coronary artery disease;
			        		
			        		
			        		
				        		Angioplasty,transluminal,percutaneous coronary;
			        		
			        		
			        		
				        		Microvolt T-wave alternation
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Circulation Journal
	            		
	            		 2018;33(1):41-45
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective: To explore the distribution features of microvolt T-wave alternation(MTWA) through exercise stress test (EST) in coronary artery disease (CAD) patients with MTWA changes after revascularization. Methods: MTWA was measured in pre-cordial ECG leads in 326 patients with suspected CAD. Based on coronary angiography and coronary CTA, the patients were divided into 4 groups: ① Control group, patients without coronary stenosis, n=101, ② Coronary stenosis<50% group, n=99, ③ 50% ≤ Coronary stenosis<70% group, n=53 and ④ Coronary stenosis ≥ 70% group, n=73; MTWA was compared among different groups. 95 patients with coronary stenosis ≥ 50%were further divided into 2 subgroups: R (right coronary)stenosis ≥ 50% subgroup, n=23 and LAD (left anterior descending branch) stenosis ≥ 50% subgroup, n=72; MTWA was respectively compared to Control group. In addition, MTWA was collected from 103 patients with percutaneous coronary intervention (PCI) as PCI group, MTWA was compared to Coronary stenosis ≥ 70% group. Results: MTWA was obviously higher in Coronary stenosis ≥ 70% group than the other 3 groups, all P<0.01. Compared with Control group, Rstenosis ≥ 50% subgroup had increased MTWA in V4-V6 pre-cordial leads, P<0.05; LAD stenosis≥50% subgroup had increased MTWA in V1-V2 pre-cordial leads, P<0.01. Compared with Coronary stenosis ≥ 70%group, PCI group showed reduced MTWA, P<0.01. Conclusion: CAD patients with severe coronary stenosis (≥70%) had increased MTWA; MTWA distribution in body surface was approximately corresponding to coronary stenosis site and PCI may decrease MTWA in CAD patients.