Observation for the Impact of Nitroglycerin on Radial Artery Structure by Optical Coherence Tomography
10.3969/j.issn.1000-3614.2018.01.006
- VernacularTitle:光学相干断层成像观察经桡动脉冠状动脉介入术后硝酸甘油对桡动脉结构的影响
- Author:
Xi-Le BI
1
;
Yan-Ming FAN
;
Yan-Bo WANG
;
Yu-Yang XIAO
;
Xin-Shun GU
;
Guo-Zhen HAO
;
Yun-Fa JIANG
;
Qing-Sheng WANG
;
Xiang-Hua FU
Author Information
1. 河北医科大学第二医院 心内科
- Keywords:
Angioplasty,transluminal,percutaneous coronary;
Radial artery;
Tomography,emission-computed,single-photon
- From:
Chinese Circulation Journal
2018;33(1):36-40
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the lumen structural changes of radial artery (RA) in patients with transradial coronary intervention and the impact of nitroglycerin on the structure by optical coherence tomography (OCT). Methods: A total of 20 patients with transradial coronary intervention were enrolled for OCT imaging to observe and compare the lumen structures of RA between the basic condition and nitroglycerin treated condition. Results: OCT imaging found that 15/20 patients had radial spasm and 1 had intimal tear. Compared to basic condition, with nitroglycerin treatment, the mean lumen diameter, lumen area and total vascular area were increased in the distal, middle and proximal portion of RA, all P<0.001; the intima-media thickness was decreased in the distal, middle and proximal portion of RA, all P<0.001; while the cross section area of tunica media, intimal thickness and extravascular membrane thickness were similar between the basic condition and nitroglycerin treated condition, all P>0.005. Conclusion: Vasodilatation drug may obviously enlarge RA lumen area and total vascular area in patients after transradial coronary intervention.
