Meta-analysis of lateral lymph node dissection for low rectal cancer
10.3969/j.issn.1009-9905.2018.04.010
- VernacularTitle:低位直肠癌侧方淋巴结清扫术的Meta分析
- Author:
Gang CHEN
1
;
Zhen-Zong TAN
;
Miao HE
;
Xian YU
;
Peng YU
;
He-Zhao ZHAO
Author Information
1. 重庆大学附属肿瘤医院/重庆市肿瘤研究所/重庆市肿瘤医院 胃肠外科 重庆400030
- Keywords:
Low rectal cancer;
Lateral lymph node dissection;
Meta-analysis
- From:
Chinese Journal of Current Advances in General Surgery
2018;21(4):287-291
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the significance of lateral lymph node dissection for low rectal cancer.Methods:Retrieval the Cochrane Library,PubMed,EMBASE,CBM,VIP,CNKI,WANFANG DATA,the time is from January 2000 to October 2015.Bring into the comparative studies about lateral lymph node dissection for low rectal cancer.Processing data using the revman 5.2 to reaserch the significance of lateral lymph node dissection for low rectal cancer.Results:9 clinical comparative studies were included in this study.The observation group was the lateral lymph node dissection group and the control group was the traditional operation group.Results showed that the length of incision of the observation group was longer [MD=-42.48,95％CI (32.92,-52.04),P＜0.00001],The amount of bleeding in observation group was more[MD=-18.72,95％Cl(5.60,31.83),P＜0.005],The local recurrence rate in the observation group was Iower[OR=-0.52,95％CI (0.38,0.71),P＜0.0001],The 3 year survival rate and the 5 year survival rate in the observation group were higher than those in the control group,the difference was statistically significant,Their combined OR and 95％CI were [OR=2.65,95％ CI (1.76,3.99),P＜0.00001] and [OR=3.57,95％ CI (2.05,6.22),P＜0.00001].Conclusion:Lateral lymph node dissection increasing operation time、hemorrhage volume and postoperative complication risk,but could increase the survival rate of the patients.
