Autophagy and neuronal diseases
10.3760/cma.j.issn.2095-4352.2018.09.016
- VernacularTitle:自噬与神经系统疾病
- Author:
Xiaolei YANG
1
;
Xi RAN
;
Xuelian LIAO
;
Li HAN
;
Yan KANG
Author Information
1. 400013,重庆市人民医院重症医学科
- Keywords:
Autophagy;
Neuronal disease;
Neurodegenerative disease;
Traumatic brain injury;
Ischemic brain injury;
Multiple sclerosis
- From:
Chinese Critical Care Medicine
2018;30(9):902-906
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a dynamic process that allows recycling of long-lived proteins and damaged organelles into biosynthetic materials for maintaining the normal cellular homeostasis. Recently, accumulating evidence has indicated that autophagy played important roles in the pathogenesis of neuronal diseases. In this article, the research progress of autophagy in the pathogenesis and regulation mechanism of common nervous system diseases were reviewed to deepen the understanding of autophagy, and arouse researchers' attention on dynamic regulation of autophagy and alleviating autophagic flow injury.
