Advances in the application of exosomes in sepsis
10.3760/cma.j.issn.2095-4352.2018.04.019
- VernacularTitle:外泌体在脓毒症中应用的研究进展
- Author:
Dan WANG
1
;
Mengna ZHANG
;
Honghong PEI
Author Information
1. 西安交通大学第二附属医院急诊科
- Keywords:
Sepsis;
Exosome;
Mesenchymal stem cell;
microRNA
- From:
Chinese Critical Care Medicine
2018;30(4):377-380
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are of great importance in cell communication and information transmission, which have become a hotspot in recent years. Most studies have focused on the transport of microRNA (miRNA) and proteins, that mediated by exosomes, as well as exosomes as a drug delivery carrier of the feasibility. Therefore, exosomes can be an important method of treatment for systemic inflammatory diseases. This article reviews the relevant literature, mainly on the related characteristics of exosomes, its association with clinical disease, and its application in sepsis.