Clinical characteristics and analysis of five cases of fulminant type 1 diabetes mellitus
10.3969/j.issn.1006-6187.2018.03.014
- VernacularTitle:五例暴发性1型糖尿病临床特点及分析
- Author:
Xinrong XIE
1
;
Qiaoling ZHAO
;
Ni ZHAO
Author Information
1. 广西壮族自治民族医院内分泌代谢科
- Keywords:
Diabetes mellitus,type 1,fulminant;
Diabetic ketoacidosis;
Islet β cell function
- From:
Chinese Journal of Diabetes
2018;26(3):249-252
- CountryChina
- Language:Chinese
-
Abstract:
Clinical and laboratory data of 5 cases of fulmiant type 1 diabetes mellitus (FTlDM) hospitalized in our department of endocrinology and metabolism from February 2014 to December 2016 were collected analyzed.All these patients characterized by acute onset and severe ketoacidosis,with course of 1-3 d.At admission,the blood glucose level was 31.8 ~ 58.9 mmol/L,HbA1c 6.0% ~ 7.5%,F-CP 0.01~0.05 nmol/L and 2 hC-P 0.02~0.05 nmol/L The pancreatic βcell function had no significant improvement after 1year.FTlDM patients have clinical features of abrupt onset,often with severe metabolic disorders,poor prognosis and seriously damaged islet β cell function.