Pulmonary Toxocariasis Mimicking Invasive Aspergillosis in a Patient with Ulcerative Colitis.
10.3347/kjp.2014.52.4.425
- Author:
Eun Jin PARK
1
;
Joon Young SONG
;
Min Ju CHOI
;
Ji Ho JEON
;
Jah yeon CHOI
;
Tae Un YANG
;
Kyung Wook HONG
;
Ji Yun NOH
;
Hee Jin CHEONG
;
Woo Joo KIM
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea. infection@korea.ac.kr
- Publication Type:Case Reports
- Keywords:
Toxocara canis;
toxocariasis;
eosinophilia;
respiratory disorder;
aspergillosis;
ulcerative colitis
- MeSH:
Albendazole/therapeutic use;
Animals;
Anthelmintics/therapeutic use;
Anti-Inflammatory Agents/therapeutic use;
Antigens, Helminth/analysis;
Colitis, Ulcerative/*complications;
Diagnosis, Differential;
Enzyme-Linked Immunosorbent Assay;
Humans;
Lung/pathology;
Lung Diseases, Parasitic/*diagnosis/*pathology;
Male;
Middle Aged;
Pulmonary Aspergillosis/diagnosis/pathology;
Steroids/therapeutic use;
Toxocara/*isolation & purification;
Toxocariasis/*diagnosis/*pathology;
Treatment Outcome
- From:The Korean Journal of Parasitology
2014;52(4):425-428
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 45-year-old-male who had underlying ulcerative colitis and presented with fever and dry cough. Initially, the patient was considered to have invasive aspergillosis due to a positive galactomannan assay. He was treated with amphotericin B followed by voriconazole. Nevertheless, the patient deteriorated clinically and radiographically. The lung biopsy revealed eosinophilic pneumonia, and ELISA for Toxocara antigen was positive, leading to a diagnosis of pulmonary toxocariasis. After a 10-day treatment course with albendazole and adjunctive steroids, the patient recovered completely without any sequelae. Pulmonary toxocariasis may be considered in patients with subacute or chronic pneumonia unresponsive to antibiotic agents, particularly in cases with eosinophilia.
