A review of animal models of post-traumatic stress disorder
10.3969/j.issn.1005-4847.2018.03.021
- VernacularTitle:创伤后应激障碍动物模型研究概况
- Author:
Chang WANG
1
;
Shuijin SHAO
;
Yupu LIU
;
Jing ZHU
Author Information
1. 上海中医药大学解剖教研室
- Keywords:
post-traumatic stress disorder;
hypothalamic pituitary adrenal axis;
stress;
animal-models
- From:
Acta Laboratorium Animalis Scientia Sinica
2018;26(3):404-409
- CountryChina
- Language:Chinese
-
Abstract:
Post-traumatic stress disorder ( PTSD) is a serious psychiatric disorder when someone suffered from a major trauma, next followed by sleep disorder, emotional and cognitive disorder and other symptoms. Over the past few decades, many stress rodents models have been developed for searching the potential pathophysiological pathways of PTSD. All models showed PTSD-like symptoms, but none of them could manifestate all the symptoms and biological changes of PTSD completely. Thus, this article makes a brief summary about the PTSD models commonly used in recent years.
