Research progress on animal models of postpartum depression and their behavior evaluation methods
10.3969/j.issn.1005-4847.2018.01.021
- VernacularTitle:产后抑郁动物模型及行为学评价方法研究进展
- Author:
Yahui TANG
1
;
Guirong ZENG
;
Lifeng WU
;
Yuhong WANG
;
Dejian JIANG
Author Information
1. 湖南省中药粉体与创新药物省部共建国家重点实验室培育基地
- Keywords:
postpartum depression;
behavior;
evaluation methods
- From:
Acta Laboratorium Animalis Scientia Sinica
2018;26(1):133-138
- CountryChina
- Language:Chinese
-
Abstract:
Postpartum depression(PPD)is one of the most common types of postpartum psychiatric syndromes. Because of the complex and changeable characteristics in PPD disease and the special period after childbirth, there are many clinical limitations in the study of this disease. Therefore,the preparation and establishment of a proper animal model closed to clinical and behavioral evaluation method plays an important role in study of its pathogenesis. This review mainly introduces the commonly used postpartum depression animal models and the behavioral evaluation method. It is hoped to provide a reference for further study of PPD pathogenesis and for the drug research and development.