Social function in long-term hospitalized patients with stable schizophrenia and its influential factors
10.3969/j.issn.1002-0152.2018.11.007
- VernacularTitle:长期住院精神分裂症稳定期患者社会功能及影响因素
- Author:
Hongmei CUI
1
,
2
;
Yanling ZHOU
;
Guannan LI
;
Dan LI
;
Bin SUN
;
Ni FAN
Author Information
1. 广州医科大学附属脑科医院(广州市惠爱医院)研究所 广州510370
2. 广州市民政局精神病院精神科
- Keywords:
Schizophrenia;
Long-term hospitalized;
Social function;
Influential factors
- From:
Chinese Journal of Nervous and Mental Diseases
2018;44(11):673-677
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore social function of long-term hospitalized patients with stable schizophrenia and its influential factors to provide scientific evidence for improving social function in long-term hospitalized patients with schizophrenia. Methods A total of 75 long-term hospitalized patients with stable schizophrenia were enrolled. The Social Functional Rating Scale (SFRS), Positive and Negative Syndrome Scale (PANSS), Insight and Treatment Attitude Questionnaire (ITAQ), Rating Scale for Extrapyramdal Side Effects (RSESE) and MATRICS (Measurement and Treatment Research to Improve Cognition in Schizophrenia) Consensus Cognitive Battery (MCCB) were used to assess social function, clinical symptoms and cognitive function of patients. Bivariate correlation analysis and linear regression were used to examine the correlations between social function and clinical symptoms as well as cognitive function. Results The average score of SFRS was (53.6 ±9.3). Linear regression analysis showed that negative symptom of PANSS (B= 0.322, P=0.009), speed of processing (B=-0.428, P<0.001), working memory (B=-0.191, P=0.020)and RESES (B=0.918, P=0.002) were significantly associated with social function. The Sobel test showed significant indirect effects between negative symptom and social function, which were significantly mediated by working memory (Z=3.367, P<0.001) and speed of processing (Z=1.995, P=0.046). Conclusion Social function of long-term hospitalized patients with stable schizophrenia is influenced by negative symptom, speed of processing, working memory and extrapyramdal side effects. There is a mediating effect between PANSS negative symptoms and SFRS in working memory and processing speed.
