A case control study of distance change of bilateral internal carotid artery in acromegaly
10.3969/j.issn.1002-0152.2018.11.001
- VernacularTitle:垂体腺瘤伴肢端肥大症患者双侧颈内动脉间距变化病例对照研究
- Author:
Changzhen JIANG
1
;
Chenyu DING
;
Xiaolong YAN
;
Yuanlong ZHANG
;
Yuanxiang LIN
;
Dezhi KANG
;
Zhangya LIN
Author Information
1. 福建医科大学附属第一医院神经外科 福州350004
- Keywords:
Acromegaly;
Internal carotid artery;
Blood vessels
- From:
Chinese Journal of Nervous and Mental Diseases
2018;44(11):641-645
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distance change of bilateral internal carotid artery in acromegalic patients. Methods Twenty patients with acromegaly were included in this study from August 2016 to March 2018 in Department of Neurosurgery of the First Affiliated Hospital of Fujian Medical University. There were 7 males and 13 females with an average age of 40.2±12.6 years (range from 21 to 62 years old). Forty sex and age matched patients with non-functional pituitary adenoma were selected as controls. The 3D printing software was used for reconstructing the internal carotid artery. Distances of the bilateral internal carotid arteries were measured on the reconstructed images. Results The maximum distance between bilateral siphon carotid ectasias (25.1±3.9 mm vs. 23.2±2.9 mm, P=0.041) and distance between bilateral lacerum segments (26.2 ±3.1 mm vs. 23.8 ±4.1 mm, P=0.022) were significantly longer in patients with acromegaly than in those without. Although the distance between bilateral cavernous segments (20.7 ±4.3 mm vs. 22.4 ±3.1 mm, P=0.076) tended to be shorter, the difference was not statistically significant. The distance between bilateral ophthalmic segments was not significantly different between the two groups (15.7±5.1 mm vs. 16.0±2.5 mm, P=0.783). Conclusion The distance of bilateral internal carotid artery of acromegalic patients is different from that of patients with non-functional pituitary adenomas. Patients with acromegaly have significantly longer distance between bilateral siphon carotid ectasias and distance between bilateral lacerum segments compared with the patients with non- functional pituitary adenomas.
