Analysis of the factors associated with seizure recurrence after a first unprovoked seizure in adults

VernacularTitle:成人首次非诱发性癫痫发作复发相关因素分析
Author: Yuanliu XIAO ¹ ; Zongmei CHEN ; Xixiang QIN ; Zhu CAO ; Xifen WU ; Wenxin LU ; Ziyi CHEN
Author Information

1. 广东省廉江市人民医院神经内科廉江 524400
Keywords: For the first time attack; Epilepsy; Recurrence; Related factors
From: Chinese Journal of Nervous and Mental Diseases 2018;44(5):257-260
CountryChina
Language:Chinese
Abstract: Objective To explore the influence factors of recurrence after a first unprovoked seizure in adults within 1 year. Methods One hundred fifty-nine adult patients with first unprovoked seizure were recruited in the study. Patients were then divided into the relapse group (n=54) and the relapse group (n=105). Statistic analysis was performed on the clinical data including gender, age, history of traumatic brain injury, electroencephalogram (EEG) and brain imaging, the form of attack time, seizures, diabetes mellitus, hypertension, coronary heart disease, hyperlipidemia disease. Results Multiariable Logistic regression analysis found that history of brain injury (P=0.033, OR=5.547), period (P=0.001, OR=33.660) in the evening, cortical lesions (P=0.004, OR=14.865) were independent risk factors for recurrence. Conclusions Adult patients with first unprovoked seizure have a high risk of one-year recurrence if the patients have a history of traumatic brain injury, the radiographic abnormalities, cortical lesions and sleep attacks.