Related factors for rapid eye movement sleep behavior disorder in early Parkinson disease
10.3969/j.issn.1002-0152.2018.02.003
- VernacularTitle:早期帕金森病患者快眼动睡眠行为障碍的相关因素
- Author:
Yushi TANG
1
;
Yujun PAN
Author Information
1. 哈尔滨医科大学附属第一医院神经内科 哈尔滨150001
- Keywords:
Parkinson disease;
Early stage;
Rapid eye movement sleep behavior disorder;
Constipation;
Restless leg syndrome
- From:
Chinese Journal of Nervous and Mental Diseases
2018;44(2):75-79
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the morbidity of rapid eye movement sleep behavior disorder(RBD) in early Parkinson disease (PD)and its related factors. Methods One hundred twenty-five early PD patients were divided into RBD group (n=51)and non-RBD group (n=74),according to the complicated with RBD.We collected the clinical data and used univariate and multivariate logistic regression methods to analyze the risk factors for rapid eye movement sleep behavior disorder in early Parkinson disease. Results The incidence of RBD is 40.80% in early PD patients.Univariate analysis showed that the age, the motor phenotype (akinetic-rigid-type), modified Hoehn-Yahr(H-Y)grade, freezing, constipation and restless leg syndrome (RLS)were significantly higher in RBD group than in non-RBD group (P<0.05). Multivariate logistic regression revealed that constipation ( P=0.001,95% CI:1.980~12.253,OR=12.912)and RLS (P=0.014, 95% CI: 1.322~12.015, OR=6.378 ) were independent influencing factors for RBD in early PD patients. Conclusion Early PD patients with constipation or RLS are prone to RBD.
