The study of relationship between intelligence impairment and interictal epileptiform discharges spreading in mesial temporal lobe epilepsy.
10.3969/j.issn.1002-0152.2018.01.002
- VernacularTitle:颞叶内侧癫痫智力损害与发作间期痫样放电扩散区域的相关性
- Author:
Zhensheng LI
1
;
Quwen GAO
;
Wei WANG
;
Jian LIN
;
Kairun PENG
;
Xiaofei GUO
;
Lihui XIA
;
Zijuan QI
Author Information
1. 中国人民解放军广州总医院癫痫科
- Keywords:
Mesial temporal lobe epilepsy;
Intelligence;
Electroencephalographic waves
- From:
Chinese Journal of Nervous and Mental Diseases
2018;44(1):6-10
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between intelligence impairment and interictal epileptiform discharges spreading in mesial temporal lobe epilepsy(mTLE)patients. Method We assessed 145 patients diagnosed as mTLE and their general materials, analyzed the relationship between intelligence impairment and interictal epileptiform discharges spreading. Results ①Patients with mTLE with longer disease course and higher frequencies of epilepsy tended to have a severe impairment in the total intelligence quotient (IQ), verbal intelligence quotient (vIQ) and performance intelligence quotient (pIQ). ② IQ of was negatively correlated with the condition that interictal epileptiform discharges spreading to the ipsilateral central and parietal region in patients with left lesion; pIQ was negatively correlated with the condition that interictal epileptiform discharges spreading to the ipsilateral frontal region, while positively correlated with the condition that interictal epileptiform discharges spreading to the ipsilateral occipital region in patients with right lesion. Conclusion ①Intelligence impairment of mTLE patients is related with courses and frequencies.②Total IQ is more severely impaired by interictal epileptiform discharges spreading to the ipsilateral central and parietal region in left mTLE patients, and the pIQ is more severely impaired by interictal epileptiform discharges spreading to the ipsilateral frontal region in right mTLE patients.
