Serum epidemiology of five strong pathogenicity human adenoviruses natural infection in Tupaia belangeri
10.3969/j.issn.1002-2694.2018.00.033
- VernacularTitle:中缅树鼩自然感染五种高致病性人腺病毒的血清流行病学分析
- Author:
Xiao LI
1
;
Zhi-Chao ZHOU
;
Xin-Gui TIAN
;
Jia-Yi LIAO
;
Ye FAN
Author Information
1. 呼吸疾病国家重点实验室
- Keywords:
tree shrew;
natural infection;
human adenoviruses;
serum epidemiology
- From:
Chinese Journal of Zoonoses
2018;34(3):243-247
- CountryChina
- Language:Chinese
-
Abstract:
In order to explore the possibility of human adenovirus infection with tree shrews,the neutralizing antibody ti-ters of five kinds of human adenoviruses (HAdv)in the serum of tree shrews were analyzed.The levels of Ad3,Ad4,Ad7, Ad14 and Ad55 neutralizing antibody were detected by virus neutralization test.The results showed that the positive rate of four adenoviruses in group B were higher than Ad4 in group E,and the positive rates respectively were Ad14 (55.88%),Ad3 (47.06%),Ad55 (29.71%),Ad7 (14.71%)and Ad4 (8.82%).The antiserum mainly mixed with Ad3,Ad14 and Ad55 anti-body.Five species of human adenovirus can be naturally infected with tree shrews.Tree shrews are used as experimental ani-mals to establish human adenovirus infection model is alternative.
