Clinical efficacy of LVIS stent combined with coil embolization of ruptured wide-necked intracranial aneurysms during the acute phase
10.3969/j.issn.1672-5921.2018.05.005
- VernacularTitle:LVIS支架联合弹簧圈栓塞急性期颅内破裂宽颈动脉瘤的临床疗效
- Author:
Tao TIAN
1
;
Tangming PENG
;
Weifeng WAN
;
Ligang CHEN
;
Changren HUANG
Author Information
1. 西南医科大学附属医院神经外科
- Keywords:
Intracranial aneurysm;
Aneurysm,ruptured;
Stents;
Embolization;
Prognosis;
LVIS stent
- From:
Chinese Journal of Cerebrovascular Diseases
2018;15(5):248-253
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the safety and efficacy of LVIS stent combined with coil embolization of ruptured wide-necked intracranial aneurysms during the acute phase.Methods From May 2014 to August 2017,the clinical and imaging data of 56 patients with ruptured wide-necked intracranial aneurysm treated with LVIS stents for acute phase assisted embolization at the Department of Neurosurgery,the Affiliated Hospital of Southwest Medical University were analyzed retrospectively.All patients were treated with LVIS stent combined with coil embolization.Immediate postoperative angiography,six months after procedure,and follow-up imaging were evaluated by Raymond grade (RS grade).The clinical follow-up results were evaluated by the modified Rankin Scale (mRS) score.Results LVIS stent combined with coil embolization was performed in 56 patients with 60 aneurysms in this group.The success rate of stent release was 100%.Immediate angiography after procedure showed that the complete embolization rate of aneurysms was 80.0% (48/60),the near complete embolization rate was 13.3 % (8/60),and the incomplete embolization rate was 6.7% (4/60).Postoperative follow-up angiography at 6 monthrevealed that the complete embolization rate of aneurysms was 87.8% (36/41),nearly complete embolization rate was 7.3% (3/41),incomplete embolization rate was 4.9% (2/41).Postoperative follow-up angiography at 12 months revealed that the complete embolization rate of aneurysms was 83.0% (39/47),and near complete embolization rate was 12.8% (6/47),and incomplete embolization rate was 4.3% (2/47).Of the 56 patients,49 were followed up clinically and 7 were lost to follow up.The average follow-up time was 13 ± 4 months.The clinical follow-up showed that the good prognosis (mRS score 0-2) rate was 87.8% (43/49).Intraoperative complications occurred in 7 cases,5 were intraoperative parent artery thrombosis and 2 were intraoperative aneurysm rupture.Conclusions LVIS stent combined with coil embolization of ruptured wide-necked intracranial aneurysms during the acute phase has good efficacy and safety.Its long-term efficacy remains to be confirmed by long-term follow-up.