Endoscopic submucosal excavation as the derivative technology of endoscopic submucosal dissection for the treatment of intestinal neuroendocrine tumor
10.3969/j.issn.1007-1989.2018.04.018
- VernacularTitle:内镜黏膜下剥离术衍生技术内镜黏膜下挖除术在消化道神经内分泌肿瘤中的应用
- Author:
Zhen-Yu ZHOU
1
;
Xiao-Yun WANG
;
Lei GONG
;
Xue-Jun TANG
;
Xiao-Bing PENG
;
Gao-Jue WU
;
Zhen HU
Author Information
1. 南京医科大学附属无锡二院 消化内科
- Keywords:
digestive tract;
neuroendocrine tumor;
endoscopic submucosal excavation
- From:
China Journal of Endoscopy
2018;24(4):85-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effect and safety of ESE (endoscopic submucosalexcavation) as the derivative technology of ESD (endoscopic submucosal dissection) for intestinal Neuroendocrinetumor. Methods A total of 23 lesions diagnosed as Neuroendocrine tumor were treated by ESE. Pathologicaldiagnosis was performed. Reverse events were recorded.Patients were followed up for recurrence andmetastasis. Results Lesions, 0.4 ~ 3.0 cm (medium size 1.0 cm) in diameter,were all resected at one ESE procedure.The operation time was 20 ~ 75 min (medium 30 min). Postoperative bleeding occurred in one case .Initiative fullthickness resection was made in one case due to the violation of muscularis propria layer. 23 cases were histologicallydiagnosed as neuroendocrine tumor, with 21 as G1 and 2 as G2, none as G3. Within 3 gastric neuroendocrine tumors,2 were type 1 and 1 was type 2. All resected samples were free of residual tumor cell in the lateral and basalmargins. Conclusion ESE is safe and efficacious for the treatment of intestinal neuroendocrine tumor.
