Research progress of Helicobacter pylori vaccine antigen
10.3969/j.issn.1000-484X.2018.06.032
- VernacularTitle:幽门螺旋杆菌候选疫苗抗原的研究进展
- Author:
Cui ZHAO
1
;
Fu-Guang ZHAO
;
Li-Ya HUANG
Author Information
1. 吉林农业大学生命科学学院
- Keywords:
Helicobacter pylori;
Vaccine;
Candidate antigen;
Immunogenicity
- From:
Chinese Journal of Immunology
2018;34(6):957-960,封3
- CountryChina
- Language:Chinese
-
Abstract:
Helicobacter pylori was separated from gastric mucosa of chronic gastritis patients for the first time in 1983, and it is the only species known to be able to survive in the human stomach. The Urase, Vacuolating cytotoxin, cytotoxin, adhesin, catalase, Outer Inflammatory Protein, duodenal ulcer promoter factor and lipopolysaccharide antigen of HP were reviewed in this paper, so that scholars can understand the recent research situation of HP antigen. The above study lays the foundation for future screening of high efficient antigen and increasing the expression of antigen, and exploring new methods of epitope binding in HP epitope vaccine.
