Innate immune cells and liver regeneration
10.3969/j.issn.1000-484X.2018.06.028
- VernacularTitle:先天免疫细胞与肝脏再生
- Author:
Xian-Guang YANG
1
;
Cong XIA
;
Shuai-Hong LI
;
Chun-Cui HE
;
Cun-Shuan XU
Author Information
1. 河南师范大学生命科学学院
- Keywords:
Liver regeneration;
Innate immune cells;
Liver disease
- From:
Chinese Journal of Immunology
2018;34(6):939-943
- CountryChina
- Language:Chinese
-
Abstract:
Liver regeneration depends on powerful immune system of ownself. TNF-α,IFN-γ,IL-6,IL-12,etc. that secreted by innate immune cells such as macrophages,dendritic cells,NK cells and NKT cells,could act on the hepatocytes and regulate liver regen-eration (LR) through corresponding signaling pathways. This article summarizes the mechanism of different innate immune cells on hep-atocytes,clarifies the recent advances of liver innate immune cellsduring liver regeneration process,lay the foundation for revealing the molecular mechanism of the development of liver regeneration and liver diseases, and for the research and development of new therapeutic methods for liver diseases.
